| Item Type | Name |
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Concept
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Adenoma, Islet Cell
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Concept
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Islets of Langerhans
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Concept
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Islets of Langerhans Transplantation
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Academic Article
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Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats.
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Academic Article
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Defects in beta-cell function in functional ovarian hyperandrogenism.
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Academic Article
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Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance.
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Academic Article
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Alterations in the kinetics of C-peptide and insulin secretion in hyperthyroidism.
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Academic Article
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NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity.
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Academic Article
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Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
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Academic Article
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Elevated plasma glucose 2 h postchallenge predicts defects in beta-cell function.
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Academic Article
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Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance.
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Academic Article
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Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes.
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Academic Article
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Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats.
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Academic Article
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Prevention of hyperglycemia in the Zucker diabetic fatty rat by treatment with metformin or troglitazone.
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Academic Article
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Maturity onset diabetes of the young (MODY).
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Academic Article
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Interactions between insulin resistance and insulin secretion in the development of glucose intolerance.
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Academic Article
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Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.
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Academic Article
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The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes.
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Academic Article
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GLP-1-induced alterations in the glucose-stimulated insulin secretory dose-response curve.
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Academic Article
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Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance.
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Academic Article
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Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism.
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Academic Article
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Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.
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Academic Article
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Evolution of beta-cell dysfunction in impaired glucose tolerance and diabetes.
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Academic Article
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Dynamics of insulin secretion in obesity and diabetes.
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Academic Article
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Glucagon-like peptide-1 stimulates insulin secretion by a Ca2+-independent mechanism in Zucker diabetic fatty rat islets of Langerhans.
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Academic Article
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Insulin production: from gene to granule.
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Academic Article
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Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.
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Academic Article
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Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha.
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Academic Article
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Temporal profiles and clinical significance of pulsatile insulin secretion.
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Academic Article
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Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young.
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Academic Article
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Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice.
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Academic Article
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Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice.
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Academic Article
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Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion.
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Academic Article
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Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times.
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Academic Article
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Calpains play a role in insulin secretion and action.
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Academic Article
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Diabetes mellitus and genetically programmed defects in beta-cell function.
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Academic Article
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Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity.
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Academic Article
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Increased islet apoptosis in Pdx1+/- mice.
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Academic Article
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A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.
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Academic Article
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Recruitment of bone marrow-derived endothelial cells to sites of pancreatic beta-cell injury.
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Academic Article
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C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001.
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Academic Article
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Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.
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Academic Article
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Persistence of oscillatory insulin secretion in denervated islet cell autografts.
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Academic Article
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Impaired beta-cell compensation to dexamethasone-induced hyperglycemia in women with polycystic ovary syndrome.
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Academic Article
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RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets.
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Academic Article
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Visualizing superoxide production in normal and diabetic rat islets of Langerhans.
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Academic Article
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Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells.
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Academic Article
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Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion.
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Academic Article
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Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice.
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Academic Article
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Diabetic pancreatic beta cells ARNT all they should be.
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Academic Article
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A significant role for histocompatibility in human islet transplantation.
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Academic Article
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Weight loss therapy improves pancreatic endocrine function in obese older adults.
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Academic Article
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Glyburide enhances the responsiveness of the beta-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus.
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Academic Article
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Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia.
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Academic Article
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In vivo pulsatility of pancreatic islet peptides.
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Academic Article
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The limitations to and valid use of C-peptide as a marker of the secretion of insulin.
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Academic Article
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Compensation in pancreatic beta-cell function in subjects with glucokinase mutations.
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Academic Article
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Ca2+ controls slow NAD(P)H oscillations in glucose-stimulated mouse pancreatic islets.
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Academic Article
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Effect of glyburide on beta cell responsiveness to glucose in non-insulin-dependent diabetes mellitus.
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Academic Article
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Natural history of multiple intrahepatic canine islet allografts during and following administration of cyclosporine.
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Academic Article
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A familial glucagonoma syndrome: genetic, clinical and biochemical features.
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Academic Article
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Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.
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Academic Article
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Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome.
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Academic Article
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C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog.
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Academic Article
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Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics.
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Academic Article
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Lack of effect of high-dose biosynthetic human C-peptide on pancreatic hormone release in normal subjects.
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Academic Article
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Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion.
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Academic Article
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Maturity-onset diabetes of the young.
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Academic Article
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Long-term follow-up of canine segmental pancreatic autografts.
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Academic Article
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Natural history of intrahepatic canine islet cell autografts.
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Academic Article
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Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
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Academic Article
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Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research.
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Academic Article
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Reduced levels of messenger ribonucleic acid for calcium channel, glucose transporter-2, and glucokinase are associated with alterations in insulin secretion in fasted rats.
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Academic Article
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Alterations in pulsatile insulin secretion in the Zucker diabetic fatty rat.
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Academic Article
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Basal insulin hypersecretion in insulin-resistant Zucker diabetic and Zucker fatty rats: role of enhanced fuel metabolism.
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Academic Article
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Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.
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Academic Article
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Portal vein thrombosis complicating islet transplantation in a recipient with the Factor V Leiden mutation.
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Academic Article
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International trial of the Edmonton protocol for islet transplantation.
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Academic Article
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Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas.
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Academic Article
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Current approaches to measurement of insulin secretion.
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Academic Article
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Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus.
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Academic Article
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Complex patterns of metabolic and Ca²? entrainment in pancreatic islets by oscillatory glucose.
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Academic Article
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BH3-only molecule Bim mediates ß-cell death in IRS2 deficiency.
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